Honey Antibacterial Effect Boosting Using Origanum vulgare L. Essential Oil

Table 6

Honey-EO interaction evaluation using the FIC.

Sample code	Escherichia coli BLSE (ATB: 87) BGN		Escherichia coli (ATB: 57) B6N		Escherichia coli (ATB: 97) BGM		Pseudomonas aeruginosa		Streptococcus faecalis		Staphylococcus aureus
	FIC	Interaction	FIC	Interaction	FIC	Interaction	FIC	Interaction	FIC	Interaction	FIC	Interaction
H1	1	A	1	A	0.75	PS	0.625	PS	0.3125	S	1.125	NI
H2	1.5	NI	1.5	NI	0.75	PS	1	A	0.5625	PS	0.625	PS
H3	1	A	1	A	0.625	PS	1.25	NI	0.5625	PS	2.0625	NI
H4	1.5	NI	2.5	NI	1.5	NI	1.25	NI	1.03125	NI	1.0625	NI
H5	1.5	NI	2.25	NI	-	-	1.5	NI	1.0625	NI	-	-
H6	1.5	NI	2.5	NI	1.125	NI	0.75	PS	1.03125	NI	1.125	NI
H7	2.5	NI	1.25	NI	1.25	NI	0.625	PS	0.53125	PS	0.531	PS
H8	2.5	NI	3	NI	-	-	1.25	NI	-	-	1.125	NI
H9	1	A	1.5	NI	1.5	NI	1.25	NI	0.5625	PS	2.125	NI
H10	1	A	1.5	NI	0.625	PS	0.625	PS	0.5625	PS	0.5625	PS
H11	1	A	1.5	NI	0.312	S	1.25	NI	0.15625	S	2.0625	NI
H12	1.5	NI	0.75	PS	1.125	NI	1.25	NI	0.53125	PS	0.5625	PS

FIC was the fractional inhibitory concentration; S = synergy, PS = partial synergy, A = additive, NI = no Interaction, and - = not effective.