Research Article

“Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018”: Antihyperglycemic Activity of Hamelia patens Jacq. Extracts

Table 5

Glucose levels and serum insulin in experimental rats.

SampleSG (mg/dL)SIN (mUI/mL)

HC112.70 ± 22.112.10 ± 1.27
DC437.50 ± 0.71###2.50 ± 1.31
DCV429.00 ± 2.831.95 ± 0.07
Metformin123.90 ± 33.91.74 ± 0.06
Acarbose142.30 ± 31.92.15 ± 0.39
CME 15093.25 ± 20.21.63 ± 0.71
CME 75156.00 ± 15.11.33 ± 0.15
CME 35153.00 ± 30.32.32 ± 1.32
FME 150117.50 ± 41.31.47 ± 0.55
FME 75168.80 ± 11.62.00 ± 0.87
FME 35162.00 ± 28.72.75 ± 0.35

(SG) concentration of glucose; (SIN) insulin; HC: healthy control; DC: diabetic control; DCV: diabetic control vehicle; CME 150: crude methanolic extract at a concentration of 150 mg/kg; CME 75: crude methanolic extract at a concentration of 75 mg/kg; CME 35: crude methanolic extract at a concentration of 35 mg/kg; FME 150: fractional methanolic extract at a concentration of 150 mg/kg; FME 75: fractional methanolic extract at a concentration of 75 mg/kg; FME 35: fractional methanolic extract at a concentration of 35 mg/kg. For the corresponding mean ± SD, ###P < 0.001 compared to the healthy control and P < 0.01 compared to the diabetic control.