Antipsoriatic Effects of Wannachawee Recipe on Imiquimod-Induced Psoriasis-Like Dermatitis in BALB/c Mice

Figure 2

Phenotypical observations of dorsal skin and ear pinna in treated mice groups. (a) Control mice (group I) with daily topical application of Vaseline on the shaved dorsal skin and ear pinna. (b) Test mice with daily IMQ-treated (5%) dorsal skin (group II) on day 7 after IMQ treatment showing psoriasis-like inflammation and erythema lesions on treated dorsal skin. (c) Ear pinna of the control mice. (d) IMQ-treated inflamed right ear pinna (marked with arrow) and the untreated left ear pinna of the same mouse. PASI scores showing intensity of (e) erythema, (f) thickness, and (g) scales of the control and treated mice dorsal skin and right ear pinna on a 0–4 point scale (none to maximum). (h) Cumulative score (erythema plus thickness plus scaling). Figures are mean score ± SD of the seven mice in each group. (i) Ear thickness of the right ear pinna. Mean ear thickness ± SD of the seven mice in each group.

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