Effects of Xin-Ji-Er-Kang on Anticardiovascular Remodeling in L-NAME Induced Hypertensive Mice and Its Potential Mechanisms

Table 3

Effects of XJEK on thoracic aorta remodeling in L-NAME induced hypertensive mice (mean ± SD, = 8~10).

Group	n	TAA (×10^3 μm^2)	LA (×10^3 μm^2)	CSA (×10^3 μm^2)	AR (μm)	Lumen (μm)	Media (μm)	Media/lumen (%)
Control	10
L-NAME	8
L-NAME + XJEK	9
L-NAME + Irbesartan	9

TAA: total aorta area; LA: lumen area; CSA: cross section area; AR: aorta radius; LR: lumen radius; MT: media thickness. The vascular remodeling of the upper thoracic aorta observed at the end of the 4th week, which could be reversed by XJEK, so could the positive drug Irbesartan. and versus control group; ^# and ^## versus L-NAME group.