Gypenosides Altered Hepatic Bile Acids Homeostasis in Mice Treated with High Fat Diet

Figure 2

Gypenosides reversed the abnormal mouse serum and hepatic lipid homeostasis. (a) Both gypenosides and simvastatin reduced the serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) levels in serum of mice treated with high fat diet. (b) Both gypenosides and simvastatin reversed the trend of lipid accumulation in mice livers. HE staining images were enlarged by 40 times. ND: normal diet group; HFD: high fat diet group; HFD+GP: gypenosides treatment on mice fed with high fat diet; HFD+ST: simvastatin treatment on mice fed with high fat diet. Data were presented as mean ± SEM. < 0.05.

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