Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Fig 7

Research Article

Immunostimulatory Effect of Zanthoxylum schinifolium-Based Complex Oil Prepared by Supercritical Fluid Extraction in Splenocytes and Cyclophosphamide-Induced Immunosuppressed Rats

Figure 7

Effect of ZPCO on immunity-associated spleen damage in Sprague Dawley (SD) rats. SD rats were oral administrated with saline, cyclophosphamide (CY; 5 mg/kg/day), and ZPCO (0, 30, 100, or 300 mg/kg/day) once daily for 28 days, after which spleen damage was analyzed histologically. Representative images of the sectioned spleens of (a) normal rats (saline treatment), (b) control rats (treated with only CY), and (c–e) ZPCO-treated rats [treated with CY and (c) 30 mg/kg, (d) 100 mg/kg, or (e) 300 mg/kg ZPCO]. Scale bar = 200 μm. CV, central vein; LN, lymph nodule; MZ, marginal zone; RP, red pulp.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.