Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay
Biochemical assays and physiological parameters results of GP treatment on nonalcoholic liver disease. Treatments with GP extracts have no obvious effects on the body weight in NAFLD mice; treatment with GP extracts 0.2 g/kg/day and 0.4 g/kg/day decreased both serum ALT and AST level; GP could increase SOD, GSH-Px level in haptic tissues. In addition, MDA levels in NAFLD liver tissue were significantly increased compared with the normal group; GP extracts can alleviate the rise of MDA in mice liver (). Compared with normal group ,,, compared with model group.