Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay

Figure 1

Biochemical assays and physiological parameters results of GP treatment on nonalcoholic liver disease. Treatments with GP extracts have no obvious effects on the body weight in NAFLD mice; treatment with GP extracts 0.2 g/kg/day and 0.4 g/kg/day decreased both serum ALT and AST level; GP could increase SOD, GSH-Px level in haptic tissues. In addition, MDA levels in NAFLD liver tissue were significantly increased compared with the normal group; GP extracts can alleviate the rise of MDA in mice liver (). Compared with normal group , , , compared with model group.

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