Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay
Picrosirius red staining results after GP extracts treatment in NAFLD (original magnification 100x). (a) The normal group had no visible Picrosirius red staining. (b) In the model group, significant Picrosirius red stain which indicated collagen deposition can be observed. (e) Treatment with GP (0.4 g/kg/day) for six weeks significantly attenuated the collagen deposition in the liver. (f) Scoring of liver fibrosis histology of NAFLD mice with GP treatment (mean ± SD). , compared with normal group, and , compared with model group.