Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Tab 2

Research Article

Treatment of Urolithiasis with Medicinal Plant Salvia miltiorrhiza: A Nationwide Cohort Study

Table 2

Incidence rates, hazard ratio, and confidence intervals of calculus surgical treatment and any bleeding disorder for calculus patients using and not using Danshen in the stratification of sex and age.

VariablesUsing Danshen in calculus patientsCrude HRAdjusted HR
NoYes
()()
EventPerson-yearsIREventPerson-yearsIR(95% CI)(95% CI)

Outcome: calculus surgical treatment
Total13704360531.425745358910.710.36 (0.33–0.4)0.34 (0.31–0.38)
Sex
 Female6152505724.54208303546.850.3 (0.26–0.35)0.29 (0.24–0.34)
 Male7551854840.703662323515.750.41 (0.36–0.47)0.39 (0.34–0.44)
Age group, years
 18–394491678426.752151978210.870.43 (0.36–0.5)0.4 (0.34–0.47)
 40–647992273935.143202815111.370.35 (0.3–0.39)0.33 (0.29–0.38)
 ≥65122408229.893956566.900.26 (0.18–0.37)0.25 (0.17–0.35)
Outcome: any bleeding disorders
Total11384416625.779175367817.080.66 (0.61–0.72)0.61 (0.56–0.67)
Sex
 Female5722534122.574633037915.240.68 (0.6–0.77)0.63 (0.56–0.71)
 Male5661882430.074542329919.490.64 (0.57–0.73)0.59 (0.52–0.67)
Age group, years
 18–392021686211.98162197868.190.68 (0.56–0.84)0.65 (0.53–0.8)
 40–646292310227.235162823818.270.67 (0.59–0.75)0.63 (0.56–0.71)
 ≥65307420273.07239565342.280.58 (0.49–0.69)0.55 (0.46–0.65)

IR, incidence rates per 1,000 person-years; HR, hazard ratio; CI, confidence interval. Adjusted HR represented adjusted hazard ratio: mutually adjusted for Danshen drug used, sex, age, diabetes mellitus, urinary tract infection, hypertension, chronic kidney disease, and gout in Cox proportional hazard regression. .

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