Bu Shen Yang Xue Prescription Has Treating Effect on Endometrial Cancer through FSH/PI3K/AKT/Gankyrin/HIF-α/cyclinD 1 Pathway in Ishikawa Cells

Figure 2

Effect of BSYX on levels of AKT, p-Akt, FSHR, Gankyrin, HIF-a, and cyclin D1 proteins in mice tumor. AKT, p-AKT, FSHR, Gankyrin, HIF-a, and cyclin D1 proteins levels were measured with Western blotting and normalized to GAPDH (a). Relative band intensities were used in order to quantify AKT, p-Akt, FSHR, Gankyrin, HIF-α, and cyclin D1 protein (b) expression levels. Data are expressed as the mean ± S.E.M. n = 10 mice in each group. P<0.01 versus the control group, P<0.05, and P<0.01 versus the model group.

(a)

(b)