Bu Shen Yang Xue Prescription Has Treating Effect on Endometrial Cancer through FSH/PI3K/AKT/Gankyrin/HIF-α/cyclinD 1 Pathway in Ishikawa Cells

Figure 6

Effect of BSYX on levels of AKT, p-Akt, FSHR, Gankyrin, HIF-a, and cyclin D1 proteins in human endometrial carcinoma Ishikawa cells. AKT, p-Akt, FSHR, Gankyrin, HIF-α, and cyclin D1 proteins levels were measured with Western blotting and normalized to GAPDH(a). Relative band intensities were used in order to quantify AKT, p-AKT, FSHR, Gankyrin, HIF-α, and cyclin D1 protein (b) expression levels. Data are expressed as the mean ±SEM n = 3 in each group. P<0.05,P<0.01 versus the control group.

(a)

(b)