Simultaneous Determination of Columbianadin and Its Metabolite Columbianetin in Rat Plasma by LC-MS/MS: Application to Pharmacokinetics of Columbianadin after Oral Administration

Table 1

MRM parameters of the three compounds.

Compounds	Q1	Q3	DP(V)	EP(V)	CE(V)	CXP (V)
Columbianetin	247.3	175.0	60	6	31	14
Columbianadin	329.3	229.3	81	3	13	20
Warfarin	309.2	163.1	60	7	20	13

DP: declustering potential; EP: entrance potential; CE: collision energy; CXP: collision cell exit potential.