Simultaneous Determination of Columbianadin and Its Metabolite Columbianetin in Rat Plasma by LC-MS/MS: Application to Pharmacokinetics of Columbianadin after Oral Administration

Table 2

The calibration curves, linearity range, and LLOQs of the assay (n=6).

Compounds	Regression; equation	r	Linearity range (ng/mL)	LLOQ (ng/mL)	Relative error; (%)	RSD (%)
Columbianetin	Y=0.0412X+0.00654	0.9988	0.1-20	0.1	104	9.8
Columbianadin	Y=0.00431X+0.00164	0.9966	0.5-20	0.5	101	9.0