Research Article

Identification of Digestive Enzyme Inhibitors from Ludwigia octovalvis (Jacq.) P.H.Raven

Table 1

Enzyme inhibition of hydroalcoholic extract, fractions, and compounds isolated from L. octovalvis leaves.

Sample Inhibition percentage
α–glucosidases
0.6 mg/mL
Pancreatic lipase
0.25 mg/mL

Acarbose50.0 ± 1.6N.A.
OrlistatN.A.50.0 ± 2.6
CsHAE80.8 ± 1.134.8 ± 2.5
LoHAE58.9 ± 5.723.6 ± 2.5
LoEAF82.8 ± 3.631.2 ± 1.9
LoAqF76.8 ± 1.915.6 ± 2.5
C1F1 (ethyl gallate)98.4 ± 2.023.2 ± 3.0
C1F260.1 ± 5.522.5 ± 3.6
C1F339.9 ± 5.64.3 ± 3.5
C1F498.9 ± 1.620.0 ± 2.3
C1F584.2 ± 5.328.2 ± 2.7
C1F679.8 ± 3.845.3 ± 0.6
C2F1 (gallic acid)98.9 ± 0.6N.A.
C3F1N.A.10.9 ± 0.3
C3F2N.A.29.3 ± 3.6
C3F3N.A.43.5 ± 4.3
C3F4N.A.36.4 ± 4.0
C4F1N.A.41.4 ± 3.2
C4F2N.A.16.6 ± 4.5
C4F3N.A.45.8 ± 5.1
C4F4P (isoorientin)N.A.55.1 ± 3.1
C4F5N.A.53.5 ± 3.7
C4F6N.A.49.1 ± 3.8
Luteolin66.3 ± 5.6N.A.

The data is indicated as the mean ± standard deviation.
N.A. = not analysed; evaluated at 5.8 µM; evaluated at 1.6 µM.