Research Article

Biological Evaluation of Different Extracts of Aerial Parts of Nepeta deflersiana and Standardization of Active Extracts Using 8-Epi-7-Deoxyloganic Acid and Ursolic Acid by Validated HPTLC Method

Table 3

Cytotoxicity of N. deflersiana extracts.

Sample Name Inhibition of cancer cells activity IC50 in µg/ml Inhibition of Non-cancer cells activity IC50 in µg/ml
SK-MELKBBT-549SK-OV-3VEROLLC-PK1

Pet. ether extractNANANANANANA
CHCl3 extractNANANANANA55
EtOAc extractNANANANANA16
n-BuOH extractNANANANANANA
Doxorubicin1.231.851.930.83>50.85

NA= no cytotoxic activity up to 100 µg/ml.