Subchronic and Genetic Safety Assessment of a New Medicinal Dendrobium Species: Dendrobium Taiseed Tosnobile in Rats

Table 8

Mammalian cell micronucleus test of DTTE in mice treated with water, DTTE, or cyclophosphamide.

Treatment	Dose (mg/kg)	Number of RET	% of MN in RET	RET/NCE (%)
24 hours
Control	-
DTTE	800
	1600
	2400
Cyclophosphamide	100
48 hours
Control
DTTE	800
	1600
	2400
Cyclophosphamide	100

All values are means ± SD (); as compared with the control group; RET: reticulocytes; NCE: normochromatic erythrocyte; and MN: micronucleus. a: cyclophosphamide via intraperitoneal injection (10 mL/kg).