6-Gingerol Activates PI3K/Akt and Inhibits Apoptosis to Attenuate Myocardial Ischemia/Reperfusion Injury
Pretreatment with 6-G (6 mg/kg) reversed infarct size, histopathological changes, and myocardial injury induced by I/R. (a) Representative images of TTC stained samples. White represents infarct area and red indicates noninfarct area. The infarct size can then be measured using Image-Pro Plus 6.0 software. (b) Infarct size score. (c) Representative images of H&E stained samples (×200). (d) Damage score. (e) Serum level of cTnT. (f) Serum level of CK-MB. Note that against the Sham group; against the I/R group.