Effect of Aidi Injection plus TACE on Hepatocellular Carcinoma: A Meta-Analysis of Randomized Controlled Trials

Table 1

Characteristics of the randomized controlled trials included in this study.

study	Number of cases			Control regimen (TACE)	Aidi intervention	therapeutic courses (days/cycles)	HCC staging	KPS score			Randomized method
	T/C	M/F	Age
Tan L et al. 2017 [5]	30/32	39/23	20-70	L-OHP+ADM+5-FU	50 ml/d	30 d2	II, III, IV	NA			NA
Dong HT et al. 2008 [6]	46/46	68/24	28 - 77	HCPT+5-FU	60 ml/d	28 d2	NA	>60			NA
Liu GY et al. 2011 [7]	30/28	40/18	47	ADM+MMC+5-FU	60 ml/d	15 d4	I, II, III		⩾70分		Random number table
Zhang GS et al. 2012 [8]	47/47	68/26	29-78	HCPT+5-FU	100 ml/d	28 d2	II, III, IV	>60			NA
Meng SX et al. 2008 [9]	75/73	97/51	55.2	THP+5-FU	50 ml/d	14 d2	II, III, IV	>60			NA
Ma T et al. 2005 [10]	36/29	5/60	47	DDP+HCPT+5-FU	50 ml/d	10 d1-2	I, II, III	>60			Medical record card number
Tao HY et al. 2017 [11]	64/64	77/59	40-75	L-OHP+EPI+5-FU	60 ml/d	28 d4	I, II, III	>50			NA
Yu B. 2013 [12]	30/30	29/31	18-65	DDP+ADM+MMC+5-FU	50 ml/d	60 d1	NA	>60			NA
A YXMGL et al. 2011 [13]	54/54	80/28	28-77	HCPT+5-FU	60 ml/d	21 d2	II, III, IV	>60			NA
Guo MA et al. 2016 [14]	36/35	47/24	55.6	ADM+MMC+5-FU	60 ml/d	14 d2	NA	NA			NA
Yang JM et al 2006 [15]	31/31	50/12	27 - 68	ADM+DDP+5-FU	50 ml/d	15 d2	NA	NA			NA
Huang J 2009 [16]	30/30	51/9	45.1	ADM+DDP+5-FU	80 ml/d	15 d2	NA	30 - 60			NA
Yuan HS et al 2010 [17]	21/21	36/6	28-74	MMC+THP+5-FU	50- 100 ml/d	10 d1-2	NA	NA			NA
Chen SC et al 2007 [18]	32/28	41/49	36-70	MMC+HU+5-FU	60 ml/d	21 d2	NA	>60			NA
Li YY et al. 2016 [19]	26/26	32/20	21-80	DDP+EPI+5-FU	40-80 ml/d	15 d2	III, IV	30 - 60			Random number table
Yang ZJ et al. 2011 [20]	30/30	53/7	26-69	MMC+EPI+HCPT+5-FU	50-100 mL	10 d3	NA	⩾70			Envelope method
Zheng Q et al. 2005 [21]	48/48	73 /25	50.6	THP+HCPT+5-FU	50 ml	28 d2	NA	>60			NA
Zhan GQ et al. 2010 [22]	32/26	46/12	21-65	MMC+HCPT+EPI+5-FU	50 ml	20 d2	II, III	>50			NA
Ma BQ. 2007 [23]	60/60	78 /42	17-82	DDP+CF+MMC+5-FU	50 ml	15 d3	NA	⩾60			NA
Wang QP et al 2008 [24]	25/23	37/11	29-68	MMC+ADM+5-FU	100 ml/d	40 d	NA	NA			NA