Research Article

In Vivo Antimalarial Activity of the 80 Methanolic Root Bark Extract and Solvent Fractions of Gardenia ternifolia Schumach. & Thonn. (Rubiaceae) against Plasmodium berghei

Table 6

Parasitemia, percentage suppression and survival time of malaria infected mice treated with crude extract of Gardenia ternifolia root barks in repository test.

Group% Parasitemia% SuppressionSurvival Time

CON21.49±0.700.006.67±0.21
GT20016.24±0.5724.47.33±0.2
GT40015.25±0.4929.08.50±0.8
GT60013.36±0.3337.89.50±0.5
CQ253.26±0.3884.816.00±0.7

Data are expressed as mean ± SEM (n=6); a, compared to CON; b, compared to CQ 25 mg/kg; c, compared to 200 mg/kg; d, compared to 400 mg/kg; e, compared to 600 mg/kg; 1p< 0.05; 2p<0.01, 3p<0.001; CON, negative control; CQ, chloroquine (positive control); GT, crude extract.