Potential Antiproliferative Activity and Evaluation of Essential Oil Composition of the Aerial Parts of Tamarix aphylla (L.) H.Karst.: A Wild Grown Medicinal Plant in Jordan

Table 3

Cytotoxicity IC₅₀ values (mean ± standard deviation (SD)) of cisplatin, doxorubicin, and T. aphylla extracts tested in a panel of cancer cell lines.

Treatment		Cytotoxicity (IC50 value: mean ± SD; μg/mL)
		MCF-7	Caco-2	Panc-1	PDL Fibroblasts
Doxorubicin		0.01 ± 0.001	0.10 ± 0.01	0.06 ± 0.01	0.14 ± 0.02
Cisplatin		1.17 ± 0.13	1.11 ± 0.15	5.97 ± 0.57	9.08 ± 0.29
T. aphylla AE		2.17 ± 0.10	479.76 ± 54.99	Nontoxic	79.99 ± 4.90
T. aphylla EE		26.65 ± 3.09	130.55 ± 12.25	88.74 ± 2.44	154.90 ± 3.29

Notes. Nontoxic within the investigated concentration range (0.1–800 μg/mL). AE: aqueous extract; EE: ethanol extract.