Modified Si-Ni-San Decoction Ameliorates Central Fatigue by Improving Mitochondrial Biogenesis in the Rat Hippocampus

Table 1

Assessment of open field test. All data were represented as the mean ±SEM (n=10), refers to P <0.05, refers to P <0.01, and refers to P =0.001 vs. CF group. △ refers to P <0.05 vs. LDM group. # refers to P <0.05 vs. MDM group. Abbreviations: CON: negative control; CQ: coenzyme Q10; HDM: high-dose modified Si-Ni-San; LDM: low-dose Si-Ni-San; MDM: medium-dose Si-Ni-San; CF: untreated central fatigue.

Parameters/group	CON	CF	LDM	MDM	HDM	CQ
Time spent in central area(s)
Total distance travelled(cm)
Number of crossing squares
Maximum continuous distance(cm)
Mean velocity(cm/s)
Vertical activity(s)
Number of grooming behavior
Time of grooming behavior(s)