Vaccinium macrocarpon Aiton Extract Ameliorates Inflammation and Hyperalgesia through Oxidative Stress Inhibition in Experimental Acute Pancreatitis

Figure 5

Effect of the hydroethanolic extract of fruits of Vaccinium macrocarpon (HEVm) on pancreatic and lung biomarkers of oxidative stress. Animals were submitted to injection of L-arginine or saline, treated with HEVm (50, 100, or 200 mg/kg) or vehicle (saline), and euthanized 72 h after pancreatitis induction. Malondialdehyde (MDA) concentrations, nonprotein sulfhydryl groups (NP-SH), carbonyl groups, and ferric reducing/antioxidant power (FRAP) were measured in pancreas ((a), (c), (e), and (g), resp.) and lung ((b), (d), (f), and (h), resp.) tissues (-6). , , and versus vehicle + saline; , , and versus vehicle + AP (one-way ANOVA followed by Bonferroni’s test).