Research Article

Probing into the Mechanism of Alkaline Citrus Extract Promoted Apoptosis in Pulmonary Fibroblasts of Bleomycin-Induced Pulmonary Fibrosis Mice

Figure 2

Inhibition of pulmonary fibroblast proliferation by CAE: primary pulmonary fibroblasts treated with CAE at various concentrations for 48 h. The density of pulmonary fibroblasts was adjusted to 1 × 105/ml, and the serum concentration was 5%. CAE was dissolved by DMSO, and the concentration of DMSO in each solution is less than 0.1%. (a) MTT analysis of inhibiting pulmonary fibroblast proliferation by CAE. All data are expressed as mean ± SD . versus normal mice, versus normal mice. (b) IC50 value of CAE inhibitory was with respect to the two kinds of pulmonary fibroblasts proliferation. All data are expressed as mean ± SD .
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