Study of Pharmacodynamic and Pharmacokinetic Interaction of Bojungikki-Tang with Aspirin in Healthy Subjects and Ischemic Stroke Patients

Table 2

Pharmacokinetic parameters among healthy subjects (phase I study).

	ASA			SA
	Aspirin + placebo	Aspirin + BJIKT		Aspirin + placebo	Aspirin + BJIKT
(ng m/ml)			N.S.			NS
(ng/ml)			N.S.			NS
(min)			N.S.			NS
1/2 (min)			N.S.			NS

BJIKT: Bojungikki-tang, ASA: acetyl salicylic acid, SA: salicylic acid, : area under the serum concentration-time curve from time 0 to 10 hours after aspirin administration, : maximum plasma concentration, : time point of maximum plasma concentration, and _1/2: terminal elimination half-life.