Study of Pharmacodynamic and Pharmacokinetic Interaction of Bojungikki-Tang with Aspirin in Healthy Subjects and Ischemic Stroke Patients

Table 5

Safety parameters among ischemic stroke patients (phase III study).

	Aspirin + placebo		Aspirin + BJIKT
	Baseline	Net change from baseline	Baseline	Net change from baseline
Liver function
AST					NS
ALT					NS
GGT					NS
T-bil					NS
ALP					NS
Protein					NS
Albumin					NS
Kidney function
BUN					NS
Cr					NS
Adverse effects
Indigestion	1		1		NS
Diarrhea	1		0		NS

BJIKT: Bojungikki-tang, AST: aspartate aminotransferase, ALT: alanine aminotransferase, GGT: gamma-glutamyl transferase, T-bil: total bilirubin, ALP: alkaline phosphatase, and BUN: blood urea nitrogen.