Development, Characterization, and Evaluation of Novel Broad-Spectrum Antimicrobial Topical Formulations from Cymbopogon martini (Roxb.) W. Watson Essential Oil

Table 4

Antimycotic activity of C. martini EOs against skin disease causing fungal pathogen using agar well diffusion technique.

Plants	Conc %v/v	Inhibition Zone Diameter (mm), including well diameter (10 mm)
		Clinical Isolates					Standard strains
		C.albicans	A. niger	M. canis	Tm	T.verrucosum	A. niger	Tm	T.rubrum
C. martini	4	31.6±2.5	29.5±0.5	90.0±0.0	90.0±0.0	90.0±0.0	70.2±2.8	90.0±0.0	90.0±0.0
	2	30.0±0.6	23.2±0.8	55.0±1.4	90.0±0.0	65.3±4.0	26.0±2.3	90.0±0.0	90.0±0.0
	1	26.0±1.0	17.2±1.2	27.0±0.6	90.0±0.0	15.5±2.0	19.2±1.5	90.0±0.0	90.0±0.0
	0,5	21.2±1.2	12.0±1.8	22.5±1.0	60.2 ±3.0	13.0±0.5	16.3±1.2	60.0±3.6	70.2±3.7
T80	0.2	0.0±0.0	0.0±0.0	0.0±0.0	0.0 ±0.0	0.0±0.0	0.0±0.0	0.0±0.0	0.0±0.0

Ca: C. albicans, An: A. niger, Mc: M. canis, Tm: T. mentagrophytes, Tr: T. rubrum, Tv: T verrucosum, Conc: concentration, T80: 2% Tween 80 as negative control, and : inhibition of the growth across the entire 90 mm plate. Data (means ± SD, n = 6) within a column with different superscripts are significantly different (p < 0.05).