Development, Characterization, and Evaluation of Novel Broad-Spectrum Antimicrobial Topical Formulations from Cymbopogon martini (Roxb.) W. Watson Essential Oil

Table 9

Physicochemical evaluation of C. martini EO topical formulations (n=3).

Property	B1	B2	B3	B4	B5
Homogeneity	Homogenous	Homogenous	Homogenous	Homogenous	Homogenous
Creaming and coalescence	Stable	Stable	Stable	Stable	Stable
Centrifugation test	Stable	Stable	Stable	Stable	Stable
Thermal cycle	Stable	Stable	Separated	Separated	Stable
Freezing and thawing	Stable	Stable	Separated	Separated	Stable
Ph	5.8± 0.4	6.21± 0.01
Fluidity	viscous	M viscous	viscous	M viscous	M viscous
Appearance	soft and fatty	fatty	Very soft and fatty	Clear, good flow	Clear, good flow
Texture	Smooth	Smooth	Smooth	Smooth	Smooth
Color	White	White	White	Opaque	Opaque
Spreadability (g.cm/sec)	14.7	10.5
Weight loss	Nil	Nil	Nil	Nil	Nil
Release	Good	Good	Poor	Poor	Poor

: not determined, B1: hydrophilic ointment base, B2: macrogol blend ointment base, B3: macrogol cream ointment base, B4: simple ointment base, and B5: white petrolatum ointment base.