Huangkui Lianchang Decoction Ameliorates DSS-Induced Ulcerative Colitis in Mice by Inhibiting the NF-kappaB Signaling Pathway
Figure 3
The HE staining (100×) of colon mucosa in control (a), DSS (b), Mesalazine (c), HLD-M (d), HLD-L (e), HLD-H (f), and the data of pathological score (g). (a) The colonic tissue from control mice showed intact mucosa without any histologic alteration. (b) DSS-induced colitis showed ulcer ( thick arrow). The colon wall structure of the Mesalazine (c) and the HLD-H (f) groups were approximately normal after treatment. (d) HLD-L treated mice do not fully recover from DSS-induced colitis, large amounts of inflammatory cells infiltrated in the colonic mucosa (arrow). (e) A few inflammatory cells infiltrated in the colonic mucosa of HLD-M group (arrow). Data are presented as the mean ± SD. P < 0.001 when compared to the control group; P < 0.001 when compared to the DSS group (n=6).