Flavonol 7-O-Glucoside Herbacitrin Inhibits HIV-1 Replication through Simultaneous Integrase and Reverse Transcriptase Inhibition

Table 1

Cytotoxicity of herbacitrin, gossypitrin, and quercetin on MT-4 and MT-2 cells. CC₅₀: concentration that causes 50% cytotoxicity, C.I.: 95% confidence interval for the CC₅₀ values obtained from the nonlinear curve fitting, n=4.

Compound	CC50 (μM) 95% C.I.
	MT-4	MT-2
Herbacitrin (1)	27.8 26.79-28.79	63.64 57.50-70.41
Gossypitrin (2)	101.0 90.83-104.98	112.56 100.29-126.35
Quercetin (3)	107.5 97.22-118.97	157.38 136.75-181.09