Research Article
The Antitumor Potential of Extract of the Oak Bracket Medicinal Mushroom Inonotus baumii in SMMC-7721 Tumor Cells
Figure 3
Western blot analysis was carried out to analyze the expression of apoptosis-related and autophagy-related proteins in SMMC-7721 cells. (a) EIB influenced the expressions of apoptosis-related protein, including Bcl-2, Bax, cytochrome c, and cleaved caspase-3. (b) EIB influenced the expressions of autophagy-related protein, including LC3-I, LC3-II, and p62. (c) EIB increased AMPK and ULK1 phosphorylation and reduced mTOR phosphorylation. EIB also increased the expression of Beclin-1. , , and versus control.
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