Huangqi Shengmai Yin Protects against Radiation-Induced Cardiac Fibrosis Injury by Regulating the TGF-β1/Smads and MMPs

Figure 3

Changes in fibrotic factors in rat injury models. (a) Immunohistochemistry was performed at one day before irradiation and day 1 and weeks 1, 2, and 4 after irradiation to reveal changes in fibrosis-related factors TGF-β1, Col1, and Col3 in irradiated rats. Magnification ×400. (b) A high dose (1.24 ml/d, HDG) of HSY was given daily to be irradiated. Immunohistochemistry was performed 4w after irradiation revealed the effect of HSY on fibrosis-related factors TGF-β1, Col1, and Col3 in irradiated rats. Magnification ×400.

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