Huangqi Shengmai Yin Protects against Radiation-Induced Cardiac Fibrosis Injury by Regulating the TGF-β1/Smads and MMPs

Table 1

The average optical density of fibrotic factors in rat models.

	Before Irradiation	25 Gy 1d	25 Gy 1w	25 Gy 2w	25 Gy 4w
TGF-β1	0.253±0.011	0.284±0.014	0.318±0.006	0.348±0.007	0.371±0.018
Col1	0.262±0.014	0.304±0.015	0.319±0.004	0.339±0.015	0.371±0.005
Col3	0.285±0.011	0. 304±0.017	0.349±0.019	0.465±0.027	0.514±0.024

The average optical density from immunohistochemistry sectioning was calculated, which indicated preliminarily fibrotic factor expression levels. p<0.05 versus before irradiation, p<0.01 versus before irradiation.