Evidence-Based Complementary and Alternative Medicine / 2019 / Article / Tab 3

Research Article

Phytochemical Analysis and Toxicity Study of Aristolochia paucinervis Rhizomes Decoction Used in Moroccan Alternative Medicine: Histopathological and Biochemical Profiles

Table 3

Lesion scores of the kidney for all groups analyzed using ANOVA test (subacute toxicity).

Histopathology of kidneyHistopathology scores of observation ANOVA test for global comparison of organ lesions among groups
(mean) per each group
control groupgroup 1group 2group 3

Tubular necrosis000.11±0.010.25±0.050.006
Hyaline necrosis000.05±0.050.19±0.040.04
Coagulation necrosis0000.22±0.170.31
Inflammatory infiltrate000.35±0.150.60±0.100.02
Extended coagulation00001
Altered tissue architecture00001
Cell vacuolization0000.25±0.250.47
Tubular degeneration000.20±0.200.31±0.190.28
Cell congestion000.10±0.030.17±0.020.04
Tubular atrophy00001
Interstitial fibrosis00001
Vascular dilation0000.16±0.030.006

Control: normal diet; group 1: normal diet + 0.5 g/kg/day extract; group 2: normal diet + 1 g/kg/day extract; group 3: normal diet + 1.5 g/kg/day extract.
: significant at 5% level.

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