Evidence-Based Complementary and Alternative Medicine

Research Article

Multiresponse Optimization of Pomegranate Peel Extraction by Statistical versus Artificial Intelligence: Predictive Approach for Foodborne Bacterial Pathogen Inactivation

Table 3

Influence of the dose of PPE addition on the growth of Staphylococcus aureus ATCC 6538 and Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 in vitro using linear model (ANOVA).


Staphylococcus aureus ATCC 6538						Salmonella enterica subsp. enterica serovar typhimurium ATCC 14028
Time (h)	0 × MIC	1 × MIC	2 × MIC	4 × MIC	8 × MIC	Time (h)	0 × MIC	1 × MIC	2 × MIC	4 × MIC	8 × MIC

0	4.00 ± 0.18^aAB	4.00 ± 0.19^aF	4.00 ± 0.15^aH	4.00 ± 0.17^aI	4.00 ± 0.18^aF	0	4.00 ± 0.16^aA	4.00 ± 0.20^aI	4.00 ± 0.16^aI	4.00 ± 0.18^aH	4.00 ± 0.19^aG
1	4.35 ± 0.21^aA	4.35 ± 0.20^aGH	4.35 ± 0.19^aHI	4.35 ± 0.20^aJ	4.35 ± 0.21^aGH	1	4.25 ± 0.17^aAB	4.25 ± 0.18^aJ	4.25 ± 0.20^aJ	4.25 ± 0.17^aI	4.25 ± 0.20^aH
2	4.80 ± 0.22^aAB	4.80 ± 0.24^aHI	4.80 ± 0.22^aJ	4.80 ± 0.19^aK	4.80 ± 0.18^aHI	2	4.50 ± 0.21^aB	4.50 ± 0.22^aK	4.50 ± 0.19^aK	4.50 ± 0.21^aK	4.50 ± 0.22^aI
3	5.02 ± 0.24^aAB	5.02 ± 0.22^aI	5.02 ± 0.25^aK	5.02 ± 0.20^aL	5.02 ± 0.23^aI	3	4.93 ± 0.24^aC	4.93 ± 0.23^aL	4.93 ± 0.24^aM	4.93 ± 0.21^aL	4.93 ± 0.24^aJ
4	5.34 ± 0.25^eAB	4.63 ± 0.22^dH	4.35 ± 0.19^cI	4.05 ± 0.19^bI	3.52 ± 0.16^aE	4	5.15 ± 0.24^dC	4.91 ± 0.22^cdL	4.75 ± 0.22^cL	4.44 ± 0.21^bK	4.00 ± 0.19^aG
5	6.57 ± 0.32^eB	4.60 ± 0.22^dH	4.20 ± 0.20^cHI	3.81 ± 0.180^bH	3.01 ± 0.14^aD	5	5.80 ± 0.27^dD	4.80 ± 0.23^cL	4.54 ± 0.21^bcK	4.21 ± 0.00^bI	3.22 ± 0.00^aF
6	7.09 ± 0.34^eBC	4.50 ± 0.21^dH	4.15 ± 0.19^cH	3.70 ± 0.17^bH	2.51 ± 0.12^aC	6	6.02 ± 0.28^dE	4.50 ± 0.21^cK	4.22 ± 0.20^bcIJ	4.00 ± 0.18^bH	2.55 ± 0.12^aE
7	8.25 ± 0.39^eBC	4.24 ± 0.18^dG	3.60 ± 0.17^cG	3.22 ± 0.15^bG	1.89 ± 0.09^aB	7	6.15 ± 0.29^dEF	4.30 ± 0.19^cJ	3.81 ± 0.18^bH	3.58 ± 0.17^bG	2.00 ± 0.08^aD
8	8.52 ± 0.16^eBC	3.91 ± 0.18^dF	3.44 ± 0.16^cF	3.00 ± 0.14^bF	1.00 ± 0.00^aA	8	6.25 ± 0.29^eF	4.00 ± 0.19^dI	3.45 ± 0.16^cG	3.00 ± 0.12^bF	1.75 ± 0.07^aC
9	9.02 ± 0.43^eC	3.65 ± 0.17^dE	3.00 ± 0.13^cE	2.61 ± 0.12^bE	1.00 ± 0.00^aA	9	6.45 ± 0.30^dFG	3.51 ± 0.16^cH	3.33 ± 0.15^cG	2.54 ± 0.12^bE	1.33 ± 0.06^aB
10	9.32 ± 0.44^dCD	3.11 ± 0.14^cD	2.74 ± 0.13^bD	2.42 ± 0.11^bD	1.00 ± 0.00^aA	10	6.55 ± 0.31^dG	3.26 ± 0.15^cG	3.00 ± 0.14^cF	2.11 ± 0.10^bD	1.00 ± 0.00^aA
11	9.56 ± 0.45^eCD	2.77 ± 0.13^dC	2.41 ± 0.11^cC	2.00 ± 0.09^bC	1.00 ± 0.00^aA	11	6.74 ± 0.32^eGH	3.04 ± 0.15^dF	2.71 ± 0.13^cE	1.75 ± 0.08^bC	1.00 ± 0.00^aA
12	9.80 ± 0.47^eCD	2.40 ± 0.11^dBC	1.90 ± 0.09^cB	1.55 ± 0.07^bB	1.00 ± 0.00^aA	12	6.85 ± 0.33^eH	2.75 ± 0.14^dE	2.42 ± 0.11^cD	1.44 ± 0.06^bB	1.00 ± 0.00^aA
14	10.52 ± 0.50^dD	2.35 ± 0.11^cBC	1.44 ± 0.07^bAB	1.22 ± 0.05^abAB	1.00 ± 0.00^aA	14	6.98 ± 0.33^dH	2.22 ± 0.10^cD	1.90 ± 0.09^bC	1.00 ± 0.00^aA	1.00 ± 0.00^aA
16	10.77 ± 0.51^dCD	2.25 ± 0.10^cB	1.20 ± 0.05^bAB	1.00 ± 0.00^aA	1.00 ± 0.00^aA	16	7.02 ± 0.30^dH	1.75 ± 0.07^cC	1.51 ± 0.07^bB	1.00 ± 0.00^aA	1.00 ± 0.00^aA
18	11.02 ± 0.52^cCD	2.14 ± 0.10^bAB	1.10 ± 0.03^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	18	7.12 ± 0.29^dHI	1.66 ± 0.07^cBC	1.25 ± 0.06^bAB	1.00 ± 0.00^aA	1.00 ± 0.00^aA
20	11.25 ± 0.50^cD	2.00 ± 0.07^bAB	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	20	7.25 ± 0.33^cHI	1.44 ± 0.06^bB	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA
22	11.36 ± 0.54^cD	1.74 ± 0.08^bAB	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	22	7.35 ± 0.33^dJ	1.25 ± 0.05^bAB	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA
24	11.50 ± 0.39^cD	1.25 ± 0.07^bA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	24	7.53 ± 0.34^bJ	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA
26	11.55 ± 0.55^cD	1.00 ± 0.06^bA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	26	7.55 ± 0.36^bJ	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA	1.00 ± 0.00^aA