A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action of the Wei Pi Xiao Decoction for the Treatment of Gastric Precancerous Lesions

Table 1

24 representative components from WPX and their corresponding predicted OB, DL, Caco-2 scores and structure.

No.	Mol ID	Molecule name	OB	DL	Caco-2	Structure	Herb
1	MOL000006	Luteolin	36.16	0.25	0.19		PHP, RMB
2	MOL000043	Atractylenolide I	37.37	0.15	1.30		AMK
3	MOL000098	Quercetin	46.43	0.28	0.05		HMM, HDW
4	MOL000211	Mairin	55.38	0.78	0.73		HMM
5	MOL000239	Jaranol	50.83	0.29	0.61		HMM
6	MOL000263	Oleanolic acid	29.02	0.76	0.59		RMB, HDW
7	MOL000296	Hederagenin	36.91	0.75	1.32		HMM, CZR
8	MOL000354	Isorhamnetin	49.60	0.31	0.31		HMM
9	MOL000358	Beta-sitosterol	36.91	0.75	1.32		PHP, HDW
10	MOL000409	Astragaloside IV	17.74	0.15	(2.22)		HMM
11	MOL000417	Calycosin	47.75	0.24	0.52		HMM
12	MOL000422	kaempferol	41.88	0.24	0.26		HMM
13	MOL000449	Stigmasterol	43.83	0.76	1.44		HDW
14	MOL000902	Curcumol	103.55	0.13	1.12		CZR
15	MOL000906	Wenjine	47.93	0.27	0.30		CZR
16	MOL001659	Poriferasterol	43.83	0.76	1.44		RMB, HDW
17	MOL001689	Acacetin	34.97	0.24	0.67		PHP
18	MOL006554	Taraxerol	38.40	0.77	1.37		PHP
19	MOL006756	Schottenol	37.42	0.75	1.33		PHP
20	MOL007111	Isotanshinone II	49.92	0.40	1.03		RMB
21	MOL007134	Danshensu	36.91	0.06	-0.27		RMB
22	MOL007151	Tanshindiol B	42.67	0.45	0.05		RMB
23	MOL007154	Tanshinone IIA	49.89	0.40	1.05		RMB
24	MOL007156	Tanshinone VI	45.64	0.30	0.48		RMB