Adverse Events Associated with Ethical Kampo Formulations: Analysis of the Domestic Adverse-Event Data Reports of the Ministry of Health, Labor, and Welfare in Japan

Table 2

Ethical Kampo formulations in the order of the number of reported adverse events.

RO	Ethical Kampo formulation	SR	GR	GF	EH	NEs
1	Shakuyakukanzoto		+			502
2	Bofutsushosan	+	+	+	+	321
3	Saireito	+	+			305
4	Yokukansan		+			275
5	Orengedokuto	+		+		144
6	Saikokaryukotsuboreito	+				134
7	Kakkonto		+		+	128
8	Hangeshashinto	+	+			118
9	Daikenchuto					116
10	Otsujito	+	+			113
11	Rikkunshito		+			107
12	Hochuekkito		+			106
13	Kamishoyosan		+	+		97
14	Shosaikoto	+	+			93
15	Bakumondoto		+			77
15	Seishinrenshiin	+	+			77
17	Shin’iseihaito	+		+		75
18	Saibokuto	+	+			69
19	Saikokeishikankyoto	+	+			68
20	Shoseiryuto		+		+	65
21	Goshajinkigan					63
22	Saikokeishito	+	+			58
23	Daisaikoto	+				52
24	Goreisan					49
25	Boiogito		+			46
26	Maoto		+		+	43
27	Unseiin	+		+		37
27	Maobushisaishinto				+	37
29	Juzentaihoto		+			36
30	Keishibukuryogan					35
30	Keigairengyoto	+	+	+		35
30	Nijutsuto	+	+			35
30	Inchinkoto			+		35
34	Tokishakuyakusan					34
35	Junchoto	+	+			28
36	Seihaito	+	+	+		27
37	Shosaikotokakikyosekko	+	+			26
38	Hangekobokuto					25
39	Tokakujokito		+			23
40	Seijobofuto	+	+	+		22
41	Ryokeijutsukanto		+			21
41	Ryutanshakanto	+	+	+		21
41	Daiokanzoto		+			21
41	Sammotsuogonto	+				21
45	Nyoshinsan	+	+			19
46	Jumihaidokuto		+			18
46	Yokukansankachimpihange		+			18
48	Kamikihito		+	+		14
49	Hachimijiogan					13
49	Keishikajutsubuto		+			13
49	Byakkokaninjinto		+			13
49	Choreito					13
53	Ninjinto		+			12
53	Chotosan		+			12
55	Kakkontokasenkyushin’i		+		+	11
56	Sokeikakketsuto		+			10
56	Gorinsan	+	+	+		10
58	Eppikajutsuto		+		+	9
58	Jidabokuippo		+			9
58	Mashiningan					9
61	Shimbuto					8
61	Makyokansekito		+		+	8
61	Keishikashakuyakuto		+			8
61	Tokiinshi		+			8
61	Ninjin’yoeito		+			8
61	Shishihakuhito		+	+		8
67	Shofusan		+			7
67	Keishikaryukotsuboreito		+			7
67	Tokishigyakukagoshuyushokyoto		+			7
67	Gokoto		+		+	7
67	Bukuryoingohangekobokuto					7
72	Goshuyuto					6
72	Tsudosan		+			6
72	San’oshashinto	+				6
72	Kanzoto		+			6
76	Anchusan		+			5
76	Hangebyakujutsutemmato					5
76	Chikujountanto		+			5
76	Kikyoto		+			5
80	Keishito		+			4
80	Shimotsuto					4
80	Shokenchuto		+			4
80	Daisaikotokyodaio	+				4
80	Keishikaryoujutsubuto		+			4
80	Shakuyakukanzobushito		+			4
86	Shigyakusan		+			3
86	Jizusoippo		+			3
86	Kososan		+			3
86	Nichinto		+			3
86	Ogikenchuto		+			3
86	Keishibukuryogankayokuinin					3
86	Keishikashakuyakudaioto		+			3
93	Goshakusan		+		+	2
93	Kanbakutaisoto		+			2
93	Saikoseikanto	+	+	+		2
93	Daibofuto		+			2
93	Unkeito		+			2
93	Inchingoreisan					2
93	Senkyuchachosan		+			2
93	Keishakuchimoto		+		+	2
93	Kakkonkajutsubuto		+		+	2
93	Ogonto	+	+			2
103	Daiobotanpito					1
103	Kihito		+			1
103	Saikanto	+	+			1
103	Choijokito		+			1
103	Shikunshito		+			1
103	Keishininjinto		+			1
103	Shimpito		+		+	1
103	Jiinshihoto		+			1
103	Choreitogoshimotsuto					1
103	Ryokyojutsukanto		+			1
103	Ryokankyomishingeninto		+			1
103	Hainosankyuto		+			1
103	Seishoekkito		+			1
103	Kyukichoketsuin		+			1
103	Kumibinroto		+			1
103	Kikyosekko					1
103	Keishikaogito		+			1
120	Shohangekabukuryoto					0
120	Mokuboito					0
120	Shichimotsukokato					0
120	Yokuininto		+		+	0
120	Shakanzoto		+			0
120	Jinsoin		+			0
120	Bukuryoin					0
120	Kyukikyogaito		+			0
120	Makyoyokukanto		+		+	0
120	Heiisan		+			0
120	Rokumigan					0
120	Jiinkokato		+			0
120	Shomakakkonto		+			0
120	Tokito		+			0
120	Sansoninto		+			0
120	Rikkosan		+			0
120	Ireito		+			0
120	Orento		+			0
120	Tokikenchuto		+			0
120	Keihito		+			0
120	Daijokito					0
120	Shireito					0
120	Choyoto					0
120	Bushirichuto		+			0
120	Shiunko					0
120	Keishikakakkonto		+			0
120	Keishikakobokukyoninto		+			0
120	Keimakakuhanto		+		+	0
120	Tokishakuyakusankabushi					0

EH: Ephedrae Herba; GF: Gardeniae Fructus; GR: Glycyrrhizae Radix; NEs: Number of reported adverse events; RO: Rank order; SR: Scutellariae Radix.