Research Article

Antitrypanosomal Effects of Zanthoxylum zanthoxyloides (Lam.) Zepern. & Timler Extracts on African Trypanosomes

Figure 4

Effect of selected fractions on cell cycle of T. brucei. (a) Dot distribution of first column represents plot of side scatter versus forward scatter; second column compares intensity of propidium iodide with forward scatter; third column compares population count of parasites with intensity of propidium iodide. Three phases of the parasite are captured in the histograms: G0-G1, first peak; S, middle trough; G2-M, second peak. Fractions were investigated at the values. (b) P values were calculated from 4 distinct counts (n=4): (P < 0.05). Error bars originate from mean percentage count ± standard deviation of the mean (Mean ± SD). ZR=Z. zanthoxyloides LZT, root; WB=butanol fraction; FD=Dichloromethane fraction; FM=Methanol fraction; CN=Negative control; ns=not significant.

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