Antitrypanosomal Effects of Zanthoxylum zanthoxyloides (Lam.) Zepern. & Timler Extracts on African Trypanosomes

Table 1

Effect of the crude extracts of Z. zanthoxyloides LZT on cell viability of T. brucei, L. donovani, P. falciparum, and Jurkat cells.

Part of plant used	MEAN   ±SEM (μg/ml)				SI
	Jurkat	T. brucei	L. donovani	P. falciparum	T. brucei	L. donovani	P. falciparum
Root	247.16±0.05	3.41±0.03	45.2±0.10	334.77±0.02	72.48	12.91	0.74
Stem bark	583.53±0.02	39.43±0.04	13.5±0.04	112.15±0.01	6.27	18.30	5.20
Leaves	95.83±0.15	27.73±0.02	>1000±0.12	>1000±0.15	3.46	<0.10	<0.96

Mean and standard errors (SE) were calculated from three distinct experiments. Selectivity index (SI) was calculated as the ratio of in Jurkat to in the respective parasite.