Eucommia ulmoides Oliv. Leaf Extract Improves Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats by Protecting Endothelial Function and Ameliorating Hypothalamic-Pituitary-Gonadal Axis Function

Figure 7

EULE restored gonadotropic hormone secretion and receptor mRNA expression. Serum levels of GnRH (a), FSH (b), LH (c), and T (d) were measured after 16 weeks of treatment. The mRNA expression levels of Gnrhr (e), Fshr (f), and Lhr (g) were analyzed by real-time PCR and are expressed as percentages of Actb levels. The data are presented as the mean ± SEM. p < 0.05, p < 0.01, and p < 0.001 versus the control group; # p < 0.05, ## p < 0.01, and ### p < 0.001 versus the DM group (n = 10 in each group).

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