Eucommia ulmoides Oliv. Leaf Extract Improves Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats by Protecting Endothelial Function and Ameliorating Hypothalamic-Pituitary-Gonadal Axis Function

Table 2

Body weights and blood glucose levels.

Index	Group	Initial	4 weeks	16weeks
Body weight (g)	Control	459.30±19.13	511.70±18.18	625.00±27.67
	DM	466.81±19.69	512.09±22.20	527.66±36.75
	Sildenafil	443.44±17.89	471.33±25.26	494.75±52.82
	EULE (0.5%)	433.55±24.06	498.77±17.57	541.66±26.17
	EULE (1%)	465.60±15.85	493.10±19.15	514.75±65.13
	EULE (2%)	478.00±16.62	511.30±16.32	576.20±17.32
Blood glucose (mmol/L)	Control	7.10±0.21	5.75±0.18	5.11±0.21
	DM	18.94±1.51	13.3±2.17	12.26±1.47
	Sildenafil	18.39±1.25	15.56±1.79	14.61±1.58
	EULE (0.5%)	20.66±1.60	15.36±2.63	14.77±1.21
	EULE (1%)	18.80±0.82	14.72±1.60	15.34±1.77
	EULE (2%)	20.59±1.69	12.44±2.15	12.17±1.34

Initial: before drug administration. 4 weeks: after drug administration for 4 weeks. 16 weeks: after drug administration for 16 weeks. Control, normal control group; DM, diabetic model group; sildenafil, diabetic group treated with sildenafil; EULE (0.5%), diabetic group treated with 0.5% EULE; EULE (1%), diabetic group treated with 1% EULE; EULE (2%), diabetic group treated with 2% EULE. Data are expressed in mean ± SEM. p < 0.05, p < 0.01, and p < 0.001versus control group (n = 10 in each group).