Research Article

Protective Effect of the Total Triterpenes of Euscaphis konishii Hayata Pericarp on Bacillus Calmette-Guérin Plus Lipopolysaccharide-Induced Liver Injury

Table 5

Effect of TTFP on TNF-α, IL-6, and NO of immunological liver injury mice (, n=10).

GroupTNF-α
(pg/mL)
IL-6
(pg/mL)
NO
(μmol/gprot)

Control63.4 ± 16.837.3 ± 8.41.47 ± 0.36
Model39.7 ± 11.0##143.6 ± 26.5##3.62 ± 0.64#
Bifendate55.6 ± 12.466.1 ± 13.31.94 ± 0.47
TTEP 50 mg/Kg42.4 ± 13.1102.4 ± 19.72.85 ± 0.43
100 mg/Kg50.7 ± 14.3 87.6 ± 15.22.30 ± 0.52
200 mg/Kg58.3 ± 12.9 55.7 ± 10.71.91 ±.051

Mouse liver samples were homogenized with icy saline and centrifuged to get the supernatants. The levels of TNF-α and IL-6 were detected with ELISA kits, while NO contents were detected by Griess Reagent Assay. , compared with the model group; #P<0.05, ##P<0.01 compared with the control group.