Ipsi- and Contralateral Moxibustion Generate Similar Analgesic Effect on Inflammatory Pain

Figure 4

Analgesic effect of ipsi- and contralateral Moxi on normal and CFA-induced pain mice. In total, F (6, 252) = 114.2, P<0.0001 (time), F (5, 42) = 254.2, P<0.0001 (group), and F (30, 252) = 24.39, P<0.0001 (interaction). There is no statistical difference among control, saline + ipsi-Moxi, and saline + contra-Moxi groups (control: saline injection group, saline + ipsi-Moxi: saline injection with ipsilateral moxibustion group; saline + contra-Moxi: saline injection with contralateral moxibustion group). CFA versus control, #P<0.01; ipsi-Moxi versus CFA, contra-Moxi versus CFA, P<0.05 (control: saline injection group; CFA: CFA injection group; ipsi-Moxi: ipsilateral moxibustion group; contra-Moxi: contralateral moxibustion group). The difference between ipsi-Moxi and contra-Moxi groups has no statistical significance.