Review Article

Cancer Survivors Could Get Survival Benefits from Postdiagnosis Physical Activity: A Meta-Analysis

Table 1

Characteristics of the studies included in the meta-analysis.

StudyYearDesignCountryStudy periodCancer typesAgeGenderStudy sizeFollow-upAdjustments or matchInterventionComparator

1Okada et al. [19]2017CohortJapan2003–2007Esophageal and gastric cancer24–95Male
Female
1604 (1053/102/338/111); death: 213
9620 (6392/516/2105/607); death: 603
ESCC: 4.4 years
GC: 6.1 years
Sex, age, year of diagnosis, BMI, smoking history, alcohol drinking history, and stage1-2 times/week
≥3 times/week
Unknown
No habit

2Abbott et al. [20]2018Case-controlUSA2010–2015Ovarian cancer20–79Female264 (130/90/44); death: 8042.7 monthsAge, stage, geographic region, number of comorbid conditions, education, and income. RPA after diagnosis is additionally adjusted for prediagnosis RPA (0, >0–9, >9 MET-hours/week)>0–9 MET-hours/week
>9 MET-hours/week
0

3Bradshaw et al. [21]2014CohortUSA1996-1997Breast cancer25–91Female1423 (349/30/181/668); death: 4205 yearsMissing data: PA, chemotherapy, and tumor size, which assumes that the missing data mechanism for PA is ignorable0.1–9.0 MET h/week
>9 MET h/week
Missing
0

4Kuiper et al. [22]2012CohortUSA1993–1998Colorectal cancer50–79Female1339 (234/166/350/312/277); death: 17111.9 yearsAdjusted for age at diagnosis, study arm, BMI, tumor stage, ethnicity, education, alcohol, smoking, and hormone therapy use>0–2.9 MET-hours/week
3.0–8.9 MET-hours/week
9.0–17.9 MET-hours/week
≥18 MET-hours/week
0

5Hardee et al. [23]2014CohortUSA1987–2002Cancers18–81 (54.4)Male
Female
2863 (PA: 1117/1746RE: 1612/1251); death: 1217.3 yearsAge, gender, and examination year, body mass index, current smoking (yes or no), heavy drinking (yes or no), hypertension (present or not), diabetes (present or not), hypercholesterolemia (yes or no), and parental history of cancer (yes or no)RE: yesRE: no
6Bao et al. [24]2015CohortChina2002–2006Breast cancer20–75Female518 (175/343); death: 1289.1 yearsAge at diagnosis (continuous variable), education (<middle school, middle school, high school, >high school), marital status, Charlson comorbidity index (0, ≥1), menopausal status (yes, no), BMI at baseline (<18, 18–24.99, 25–29.99, ≥30), soy protein intake (Q1–Q4), tea consumption at baseline (yes, no), chemotherapy (yes, no), radiotherapy (yes, no), and TNM stage (I, II, III, unknown)YesNo

7Gunnell et al. [25]2017CohortAustralia2004–2011Cancers68Male
Female
1667 (439/460/384/384); death: 1358.8 yearsAge at survey, sex, smoking category, long-term risky drinking category, body mass index category, daily fruit and vegetable intake, survey year, self-reported diabetes, SF-8 mental health component score, SF-8 physical health component score, and previous cancer type<150 min LTPA/week
150–359 min LTPA/week
360 + min LTPA/week
No LTPA

8Baade et al. [26]2011CohortAustralia2003–2008Colorectal cancer20–70+Male
Female
1825 (748/484/593); death: 4624.9 yearsNot mentionedInsufficiently active
Sufficiently active
Sedentary

9Irwin et al. [27]2008CohortUSA1995–2004Breast cancer>18Female688 (114/297/277); death: 532.5 yearsAge, race, disease stage, initial treatment, tamoxifen use, body mass index, and fruit/vegetable servings per day>0–8.9 MET-h/wk
≥9 MET-h/wk
0 MET-h/wk

ESCC: esophageal cancer; GC: gastric cancer; PA: physical activity; RE: resistance exercise.