The Guizhi Gancao Decoction Attenuates Myocardial Ischemia-Reperfusion Injury by Suppressing Inflammation and Cardiomyocyte Apoptosis

Figure 2

Effect of GGD treatment on histopathological changes in myocardial tissues of different groups. Control group showed obvious integrity of myocardial membrane without any inflammatory infiltration, cardiac necrosis, or infarction. I/R group showed distorted cardiac muscles, local swelling, inflammatory infiltration, and cardiac necrosis. Treatment with TMZ and GGD at doses of 1.8g/kg and 3.6g/kg reduced inflammatory infiltration and cardiac necrosis. Photomicrographs were taken at ×200 magnification.