Apoptotic Effects of Xanthium strumarium via PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma

Figure 5

Effects of XS-5 and XS-6 on the PI3K/AKT signaling pathway of HCC cells. The effects of XS-5 and XS-6 on the expression levels of AKT, mTOR, GSK3β, and 4EBP1 and their phosphorylated forms were determined by western blot analysis. Hep3B and Huh-7 cells were treated with XS-5 and XS-6 (100 μg/ml) for 6 h.