Research Article
Jieduquyuziyin Prescription-Treated Rat Serum Suppresses Activation of Peritoneal Macrophages in MRL/Lpr Lupus Mice by Inhibiting IRAK1 Signaling Pathway
Figure 3
JP downregulates LPS-induced signaling pathway in peritoneal macrophages of MRL/lpr mice. (a) The expression alterations in IRAK1 and NF-κB mRNA. (b) The expression alterations in phosphorylation and nonphosphorylation of IRAK1 and NF-κB protein. (c) The protein expression alterations in TRAF6, IKBα, p-IKBα, and IKKα + IKKβ. (d) The related protein bands. Values are expressed as mean ± SD of three independent experiments. and versus control cells; and versus LPS-treated cells.
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