Active Ingredients and Action Mechanisms of Yi Guan Jian Decoction in Chronic Hepatitis B Patients with Liver Fibrosis

Table 1

Active ingredients of the YGJD in the treatment of CHB-related liver fibrosis.

ID	Out DC	Compound name	Origin	Molecular formula	Cluster
YGJ510	65	Diosgenin	Ophiopogonis Radix	C27H42O3	3
YGJ009	60	Belladonnine	Lycii Fructus	C34H42N2O4	Isolated
YGJ386	59	6-Deacetyloxy-7-deacetylchisocheton	Toosendan Fructus	C26H36O4	Isolated
YGJ775	55	24-Methylenecycloartanol ferulate	Lycii Fructus	C41H60O4	Isolated
YGJ061	54	Methylophiopogonanone A	Ophiopogonis Radix	C19H16O6	15
YGJ230	50	Mesendanin M	Toosendan Fructus	C30H44O4	6
YGJ833	46	Marmesinin	Glehniae Radix	C20H24O9	Isolated
YGJ260	44	Meliasenin X	Toosendan Fructus	C30H48O5	7
YGJ303	43	3,3′Z-6.7′,7.6′-diligustilide	Angelica Sinensis Radix	C24H28O4	Isolated
YGJ205	42	Mesendanin J	Toosendan Fructus	C28H40O8	48
YGJ377	42	Trichilinin E	Toosendan Fructus	C35H42O8	12
YGJ812	41	Lantadene A	Lycii Fructus	C35H54O5	Isolated
YGJ019	40	Ophiopogonone A	Ophiopogonis Radix	C18H14O6	14
YGJ485	39	Lupeol	Glehniae Radix; Lycii Fructus	C30H50O	2
YGJ051	39	N-p-coumaroyltyramine	Ophiopogonis Radix	C18H15NO4	Isolated
YGJ253	38	Meliasenin W	Toosendan Fructus	C30H50O4	9
YGJ160	38	Meliasenin P	Toosendan Fructus	C31H50O4	8
YGJ320	35	Nimbolinin C	Toosendan Fructus	C38H46O9	11
YGJ602	32	Levistolide A	Angelica Sinensis Radix	C24H28O4	30
YGJ235	31	Mesendanin U	Toosendan Fructus	C32H50O6	Isolated
YGJ012	30	8-Geranyloxypsoralen	Glehniae Radix	C21H22O4	35
YGJ624	28	Campesteryl ferulate	Lycii Fructus	C38 H56 O4	53
YGJ566	22	24-Methylenecycloartanol	Lycii Fructus	C31H52O	5
YGJ690	21	12-O-nicotinoylisolineolone	Lycii Fructus	C27H35NO6	Isolated
YGJ723	20	Isotetandrine	Angelica Sinensis Radix	C38H42N2O6	Isolated
YGJ486	18	Sitogluside	Rehmanniae Radix; Glehniae Radix; Angelica Sinensis Radix	C35H60O6	51
YGJ414	18	Toosendanic acid A	Toosendan Fructus	C30H48O4	6
YGJ005	17	2′-Hydroxymatteucinol	Ophiopogonis Radix	C18H18O6	Isolated
YGJ006	16	Taurochenodeoxycholic acid	Lycii Fructus	C26H45NO6S	Isolated
YGJ358	16	2-Hydroxy-3-(3-methylbut-2-enyl) furo[3,2 g] chromen-7-one	Glehniae Radix	C16H14O4	Isolated