Naomaitai Ameliorated Brain Damage in Rats with Vascular Dementia by PI3K/PDK1/AKT Signaling Pathway
Naomaitai can reduce myelin demyelination and improve white matter damage in VD rats. LFB staining was utilized to observe the damage of white matter nerve fibers and the loss of myelin sheath. Immunofluorescence method was used to determine the MBP expression in white matter of rats. (a) LFB staining (bar, 50μm); (b) the expression of MBP determined by Immunofluorescence method (bar, 50μm). P<0.05 vs. Sham group; #P<0.05 vs. VD group.
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