Research Article

Momordica charantia (Indian and Chinese Bitter Melon) Extracts Inducing Apoptosis in Human Lung Cancer Cell Line A549 via ROS-Mediated Mitochodria Injury

Figure 1

Cell apoptosis observed using Hoechst 33358 staining. A549 cells were treated with M. charantia extracts for 24 hrs. Treated A549 cells exhibited morphological changes in the nuclei with stronger blue fluorescence (typical of apoptosis) than non-apoptotic cell. Photographs were taken under a fluorescence microscope (200×, original magnification). The yellow arrows represent apoptotic cells.