Antihypertensive Activity of Leersia hexandra Sw. (Poaceae) Aqueous Extract on Ethanol-Induced Hypertension in Wistar Rat

Figure 5

Effects of Leersia hexandra aqueous extract on histomorphometry (a) and histology (b) of the aorta (hematoxylin and eosin, x100). Each bar represents mean ± SEM of 5 rats. NTR: normotensive rats receiving distilled water (10 mL/kg), HTR: hypertensive rats receiving distilled water (10 mL/kg) and ethanol (5 g/kg), L h 100 and L h 200: hypertensive rats receiving ethanol and extract of Leersia hexandra at doses of 100 and 200 mg/kg, and Nif. 10: hypertensive rats receiving nifedipine at the dose of 10 mg/kg; A: adventitia, I: intima, and M: media; 2: p < 0.01 and 3: p < 0.001: significant difference compared to normotensive rats; c: p < 0.001: significant difference compared to hypertensive rats.

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(b)